Receptor Summary

General Information
OR1C1 (OR1C1_HUMAN)
Olfactory Receptor Family 1 Subfamily C Member 1 [Source:HGNC Symbol;Acc:HGNC:8182]
Homo sapiens
OR1C1
UniProt | Entrez Gene
Sequence (314 pc)
         10         20         30         40         50         60         70         80         90        100
 MEKRNLTVVR EFVLLGLPSS AEQQHLLSVL FLCMYLATTL GNMLIIATIG FDSHLHSPMY FFLSNLAFVD ICFTSTTVPQ MVVNILTGTK TISFAGCLTQ
        110        120        130        140        150        160        170        180        190        200
 LFFFVSFVNM DSLLLCVMAY DRYVAICHPL HYTARMNLCL CVQLVAGLWL VTYLHALLHT VLIAQLSFCA SNIIHHFFCD LNPLLQLSCS DVSFNVMIIF
        210        220        230        240        250        260        270        280        290        300
 AVGGLLALTP LVCILVSYGL IFSTVLKITS TQGKQRAVST CSCHLSVVVL FYGTAIAVYF SPSSPHMPES DTLSTIMYSM VAPMLNPFIY TLRNRDMKRG
        310        320        330        340        350        360        370        380        390        400
 LQKMLLKCTV FQQQ

Protein Diagram

When using this 2D protein diagram,please cite:
Protter: interactive protein feature visualization and integration with experimental proteomic data. Omasits U, Ahrens CH, Müller S, Wollscheid B. Bioinformatics. 2014 Mar 15;30(6):884-6. doi: 10.1093/bioinformatics/btt607
Click here to view the paper: Protter paper

3D Model
GeneCards: OR1C1
Click here to download PDB file

Citations:
Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem 23 (2015) 4082-4091. doi: 10.1016/j.bmc.2015.04.025

3D Visualizer: NGL, A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402

Jumper, J., Evans, R., Pritzel, A. et al. Highly accurate protein structure prediction with AlphaFold. Nature 596, 583–589 (2021). doi: 10.1038/s41586-021-03819-2

Mihaly V., Stephen A., Mandar D. et al. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models, Nucleic Acids Research, Volume 50, Issue D1, 7 January 2022, Pages D439–D444, doi: 10.1093/nar/gkab1061

Known Ligands of OR1C1 in FSBI-DB
Category
Name
PUBCHEM
Structure
Reference

Phenylpropanoids and polyketides

chromen-2-one

323

details
Show Ligands in Similarity Network
Ectopic Expression

Ectopic expression of some Receptors in a variety of tissues was drawn using R gganatogram package, based on a comprehensive expression analysis with Next Generation Sequencing (NGS) technique (View more). Expression data are taken from the table-Expression profile of all genes in 16 different human tissues. Original values are added by one to show a log10 transformed profile.


Citation:
Expression Profile of Ectopic Olfactory Receptors Determined by Deep Sequencing Caroline Flegel,Stavros Manteniotis,Sandra Osthold,Hanns Hatt,Günter Gisselmann Published: February 6, 2013