Receptor Summary

General Information
OR5AC2 (O5AC2_HUMAN)
Olfactory Receptor Family 5 Subfamily AC Member 2 [Source:HGNC Symbol;Acc:HGNC:15431]
Homo sapiens
OR5AC2
UniProt | Entrez Gene
Sequence (309 pc)
         10         20         30         40         50         60         70         80         90        100
 MDISEGNKTL VTEFVLTGLT DRPWLHVLFF VVFLVVYLIT MVGNLGLIVL IWNDPHLHMP MYLFLGGLAF SDACTSTSIT PRMLVNFLDK TAMISLAECI
        110        120        130        140        150        160        170        180        190        200
 TQFYFFASSA TTECFLLVMM AYDRYVAICN PLLYPVMMSN KLSAQLLSIS YVIGFLHPLV HVSLLLRLTF CRFNIIHYFY CEILQLFKIS CNGPSINALM
        210        220        230        240        250        260        270        280        290        300
 IFIFGAFIQI PTLMTIIISY TRVLFDILKK KSEKGRSKAF STCGAHLLSV SLYYGTLIFM YVRPASGLAE DQDKVYSLFY TIIIPLLNPF IYSLRNKKVM
        310        320        330        340        350        360        370        380        390        400
 HALRRVIRK

Protein Diagram

When using this 2D protein diagram,please cite:
Protter: interactive protein feature visualization and integration with experimental proteomic data. Omasits U, Ahrens CH, Müller S, Wollscheid B. Bioinformatics. 2014 Mar 15;30(6):884-6. doi: 10.1093/bioinformatics/btt607
Click here to view the paper: Protter paper

3D Model
GeneCards: OR5AC2
Click here to download PDB file

Citations:
Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem 23 (2015) 4082-4091. doi: 10.1016/j.bmc.2015.04.025

3D Visualizer: NGL, A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402

Jumper, J., Evans, R., Pritzel, A. et al. Highly accurate protein structure prediction with AlphaFold. Nature 596, 583–589 (2021). doi: 10.1038/s41586-021-03819-2

Mihaly V., Stephen A., Mandar D. et al. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models, Nucleic Acids Research, Volume 50, Issue D1, 7 January 2022, Pages D439–D444, doi: 10.1093/nar/gkab1061

Known Ligands of OR5AC2 in FSBI-DB
Category
Name
PUBCHEM
Structure
Reference

Benzenoids

4-hydroxy-3-methoxybenzaldehyde (vanillin)

1183

details
Show Ligands in Similarity Network
Ectopic Expression

Ectopic expression of some Receptors in a variety of tissues was drawn using R gganatogram package, based on a comprehensive expression analysis with Next Generation Sequencing (NGS) technique (View more). Expression data are taken from the table-Expression profile of all genes in 16 different human tissues. Original values are added by one to show a log10 transformed profile.


Citation:
Expression Profile of Ectopic Olfactory Receptors Determined by Deep Sequencing Caroline Flegel,Stavros Manteniotis,Sandra Osthold,Hanns Hatt,Günter Gisselmann Published: February 6, 2013