Welcome to FlavorDB

Content

Generals
Classification
Quality
Toxicity & Safety
Receptors

Compound Summary

General Compound Information

Cromolyn

Click to view/hide 3D structure

Description

Cromoglycic acid is a dicarboxylic acid that is the bis-chromone derivative of glycerol. It is effective as a mast cell stabilizer. It has a role as a calcium channel blocker and an anti-asthmatic drug. It is a dicarboxylic acid and a member of chromones. It is a conjugate acid of a cromoglycate(1-).

Synonyms

cromolyn; Cromoglicic acid; 16110-51-3; Cromoglycic acid; Cromoglycate;

Cromoglicate;Acidum cromoglicicum;Intal;5,5'-((2-Hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylic acid);Acido cromoglicico;Acide cromoglicique;Cromo-Comod;Aarane;Acide cromoglicique [INN-French];Acido cromoglicico [INN-Spanish];Acidum cromoglicicum [INN-Latin];5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid;Y0TK0FS77W;CHEBI:59773;R03BC01;Aararre;Frenasma;Lomudal;Lomudas;Lomusol;Nalcrom;Nebulasma;Rynacrom;Nasmil;1,3-Bis(2-carboxychromon-5-yloxy)-2-hydroxypropane;Cromo asma aerosol;Cromoglicic acid (INN);Dinatrium cromoglicicum;CROMOGLICIC ACID [INN];1,3-Di(2-carboxy-4-oxochromen-5-yloxy)propan-2-ol;4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo-;4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-;5,5'-((2-Hydroxypropane-1,3-diyl)bis(oxy))-bis(4-oxo-4H-chromene-2-carboxylic acid);5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylic acid);FPL 670;5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acid;5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid;Sodium Chromoglycate;5,5'-(2-Hydroxytrimethylenedioxy)bis(4-oxochromene-2-carboxylic acid);NSC109500;NCGC00021142-02;UNII-Y0TK0FS77W;Chromoglycate;Chromolyn;Cromoglicic acid [INN:BAN];cromoglicic-acid;HSDB 3308;5-(3-((2-Carboxy-4-oxo-4H-chromen-5-yl)oxy)-2-hydroxypropoxy)-4-oxo-4H-chromene-2-carboxylic acid;EINECS 240-279-8;Cromo-Comod (TN);Spectrum_000852;CROMOLYN [HSDB];CROMOLYN [MI];CROMOLYN [VANDF];Cromolyn;Cromoglicic acid;Prestwick0_000812;Prestwick1_000812;Prestwick2_000812;Prestwick3_000812;Spectrum2_001137;Spectrum3_000367;Spectrum4_000302;Spectrum5_000791;SCHEMBL3865;Oprea1_077850;BSPBio_000703;BSPBio_002093;KBioGR_000884;KBioSS_001332;BIDD:GT0397;DivK1c_000857;SPBio_001033;SPBio_002624;BPBio1_000775;CHEMBL428880;GTPL7608;DTXSID4022860;KBio1_000857;KBio2_001332;KBio2_003900;KBio2_006468;KBio3_001313;CROMOGLICIC ACID [WHO-DD];NINDS_000857;HY-B1619;ZINC1530788;BDBM50440033;MFCD00864784;AKOS015961001;DB01003;4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxytrimethylene)dioxy)bis(4-oxo-;IDI1_000857;ETHYLENEDIAMINEDI-L-(+)-TARTRATE;NCGC00021142-01;NCGC00159523-01;AC-12785;BS-51003;NCI60_000229;SBI-0051323.P003;CS-0013552;FT-0601561;1,3-bis(2-carboxychromon-5-yloxy)propan-2-ol;C06928;D07753;E78436;1,3-bis-(2-carboxychromon-5-yloxy)propan-2-ol;A922357;EN300-19766015;Q416427;J-009783;BRD-K20920669-304-06-7;4H-1-Benzopyran-2-carboxylic acid, 5, {5'-[(2-hydroxytrimethylene)dioxy]bis(4-oxo-,};5,5'-((2-HYDROXYTRIMETHYLENE)DIOXY)BIS(4-OXO-4H-1-BENZOPYRAN-2-CARBOXYLATE);5,5'-(2-hydroxypropane-1,3-diyl)bis(oxy)bis(4-oxo-4H-chromene-2-carboxylic acid);105878-73-7;4H-1-Benzopyran-2-carboxylic acid, {5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-,};4H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 5,5'-((2-HYDROXY-1,3-PROPANEDIYL)BIS(OXY))BIS(4-OXO-);5-[3-(2-carboxy-4-oxo-chromen-5-yl)oxy-2-hydroxy-propoxy]-4-oxo-chromene-2-carboxylic acid;

FlavorDB ID

13

PUBCHEM ID

2882

Molecular Weight

468.4

Molecular Formula

C23H16O11

Openeye Can Smiles

C1=CC2=C(C(=C1)OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)O)O)C(=O)C=C(O2)C(=O)O

IUPAC Inchikey

IMZMKUWMOSJXDT-UHFFFAOYSA-N

Network

Shown in network

Similarity

Show/Hide similarity panel

Compound Classification

Classification (Parent Nodes)

ClassyFire Ontology

Compound Quality

Quality information of this compound is not available!

Compound Toxicity and Food Additive Safety (OFAS)

Toxicity Summary
Link to the Distributed Structure-Searchable Toxicity (DSSTox) Database
Symptoms of overdose include cough, nasal congestion, nausea, sneezing and wheezing.
Source: DrugBank or Hazardous Substances Data Bank (HSDB)

Receptors

Receptor	REFERENCE	EC50 [µM]	Effective Concentration [µM]
TAS2R7	details	Activated
TAS2R43	details	Activated
TAS2R20	details	Activated

Consensus Spectra

Spectrum Type	Spectrum View	Description	Polarity
Experimental LCMS	view	LCMS_Positive	positive