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Compound Summary

General Compound Information

(E,E)-2,4-heptadienal

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Description

(E,E)-hepta-2,4-dienal is a heptadienal in which the two double bonds are located at positions 2 and 4 (the E,E-geoisomer). It has a role as a flavouring agent.

Synonyms

2,4-HEPTADIENAL; (2E,4E)-Hepta-2,4-dienal; trans,trans-2,4-Heptadienal; 4313-03-5; 5910-85-0;

Trans-2-trans-4-Heptadienal;(E,E)-2,4-Heptadienal;2,4-Heptadienal, (2E,4E)-;2,4-Heptadienal, (E,E)-;(E,E)-2,4-Heptadien-1-al;(2E,4Z)-2,4-heptadienal;FEMA No. 3164;(2E,4E)-2,4-Heptadienal;trans |trans|-24-Heptandienal;2,4-Heptadien-1-al;(e,e)-hepta-2,4-dienal;VY79R3SU8X;trans,trans-Hepta-2,4-dienal;2,4-Heptdienal;BRN 1739522;EINECS 227-627-4;EINECS 224-328-0;starbld0000834;UNII-VY79R3SU8X;2,4-(E,E)-Heptadienal;(e, e)-2,4-heptadienal;Hepta-2(E),4(E)-dienal;SCHEMBL231267;SCHEMBL231268;(2Z,4E)-2,4-Heptadienal;trans, trans-2,4-Heptandienal;CHEMBL2269080;DTXSID9064057;(E)-2,(E)-4- Heptadienal;2,4-HEPTADIENAL [FHFI];DTXSID60872846;CHEBI:132837;(2E,4E)-2,4-Heptadienal #;ALL-TRANS-2,4-HEPTADIENAL;ZINC2567938;LMFA06000024;MFCD00007005;(E),(E)-2,4-HEPTADIENAL;AKOS015900514;CS-W013668;trans,trans-2,4-Heptandienal, >=88%;2,4-Heptadienal, technical grade, 90%;BS-16809;LS-13292;(E),(E)-2,4-HEPTADIENAL [FCC];DB-003790;H0681;EN300-1829152;A826167;Q-100006;Q27292092;trans,trans-2,4-Heptadienal (Technical Grade, 90per cent);

FlavorDB ID

2845

PUBCHEM ID

Molecular Weight

110.15 Molecular Formula

C7H10O

Openeye Can Smiles

CCC=CC=CC=O

IUPAC Inchikey

SATICYYAWWYRAM-VNKDHWASSA-N

Network

Similarity

CATEGORY	QUALITY	THRESHOLD	OCCURENCE	REFERENCE
smell	fatty, flowery	2.905e-4 µmol/L	green tea	details
smell	rancid fish, fishy, oily		water	details
smell	rancid fish, fishy, oily	4.542e-2 µmol/L	water	details

Toxicity Summary
Link to the Distributed Structure-Searchable Toxicity (DSSTox) Database

Food Additive Safety (OFAS)
2,4-HEPTADIENAL is used for FLAVORING AGENT OR ADJUVANT. More food additive safty information please view GRAS report.

EFSA's chemical Hazards Database : OpenFoodTox
This compound is found in OpenFoodTox with the name: Hepta-2,4-dienal

Reference point : Defined point on an experimental dose–response relationship for the critical effect. This term is synonymous to Point of departure (USA). Reference points include the lowest or no observed adverse effect level (LOAEL/NOAEL) or benchmark dose lower confidence limit (BDML), used to derive a reference value or Margin of Exposure in human and animal health risk assessment. In the ecological area, these include lethal dose (LD50), effect concentration (EC5/ECx), no (adverse) effect concentration/dose (NOEC/NOAEC/NOAED), no (adverse) effect level (NEL/NOAEL), hazard concentration (HC5/HCx) derived from a Species Sensitivity Distributions (SSD) for the ecosystem (EFSA Scientific Committee,2018). Citation: DOI 10.5281/zenodo.4740174

Reference point information of this compound is not available!

Reference Value

Reference Value : The estimated maximum dose (on a body mass basis) or the concentration of an agent to which an individual may be exposed over a specified period without appreciable risk. Reference values are established by applying an uncertainty factor to the reference point. Examples of reference values in human health include acceptable daily intake (ADI) for food and feed additives, and pesticides, tolerable upper intake levels (UL) for vitamins and minerals, and tolerable daily intake (TDI) for contaminants and food contact materials. For acute effects and operators, the acute reference dose (ARfD) and the acceptable operator exposure level (AOEL). In animal health and the ecological area, these include safe feed concentrations and the Predicted no effect concentration (PNEC) respectively (EFSA Scientific Committee, 2018). Citation: DOI 10.5281/zenodo.4740174

OUTPUT ID	ASSESSMENT	QUALIFIER	VALUE	UNIT	POPULATION
3258	TTC Cramer Class I	=	30	µg/kg bw/day	Consumers

Genotoxicity

Author	YEAR	OUTPUT ID	Genotoxicity
EFSA CEF	2009	2290	Ambiguous
EFSA CEF	2014	2484	Ambiguous
EFSA CEF	2018	3045	Negative
EFSA FAF	2019	3258	Negative

EFSA Outputs

Output ID	Title	DOI	Published
2290	Flavouring Group Evaluation 203: alpha,beta-Unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated double bonds and with or without additional non-conjugated double bonds. Scientific Opinion of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)	doi:10.2903/j.efsa.2009.877	01Apr2009
2484	Scientific Opinion on Flavouring Group Evaluation 203, Revision 1n(FGE.203Rev1): alpha,beta-Unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated doublebonds and with or without additional non-conjugated double-bonds	doi:10.2903/j.efsa.2014.3626	10Apr2014
3045	Scientific Opinion on Flavouring Group Evaluation 203, Revision 2 (FGE.203Rev2): alpha,beta-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.4 of FGE.19 with two or more conjugated double-bonds and with or without additional non-conjugated double-bonds	doi:10.2903/j.efsa.2018.5322	20Jul2018
3258	Scientific Opinion on Flavouring Group Evaluation 70, Revision 1 (FGE.70Rev1): consideration of aliphatic, linear, alpha,beta-unsaturated, di- and trienals and related alcohols, acids and esters evaluated by JECFA (61st-68th-69th meeting)	doi:10.2903/j.efsa.2019.5749	17Jul2019

Receptors

Receptor information of this compound is not available!

Consensus Spectra

Spectrum Type	Spectrum View	Description	Polarity
Experimental GCMS	view	GCMS	positive

Content

Compound Summary

(E,E)-2,4-heptadienal

Description

(E,E)-hepta-2,4-dienal is a heptadienal in which the two double bonds are located at positions 2 and 4 (the E,E-geoisomer). It has a role as a flavouring agent.

Synonyms

2,4-HEPTADIENAL; (2E,4E)-Hepta-2,4-dienal; trans,trans-2,4-Heptadienal; 4313-03-5; 5910-85-0;

FlavorDB ID

2845

PUBCHEM ID

5283321

Molecular Weight

110.15

Molecular Formula

C7H10O

Openeye Can Smiles

CCC=CC=CC=O

IUPAC Inchikey

SATICYYAWWYRAM-VNKDHWASSA-N

Network

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Similarity

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Content

Compound Summary

(E,E)-2,4-heptadienal

Description

(E,E)-hepta-2,4-dienal is a heptadienal in which the two double bonds are located at positions 2 and 4 (the E,E-geoisomer). It has a role as a flavouring agent.

Synonyms

2,4-HEPTADIENAL; (2E,4E)-Hepta-2,4-dienal; trans,trans-2,4-Heptadienal; 4313-03-5; 5910-85-0;

FlavorDB ID

2845

PUBCHEM ID

5283321

Molecular Weight

110.15

Molecular Formula

C7H10O

Openeye Can Smiles

CCC=CC=CC=O

IUPAC Inchikey

SATICYYAWWYRAM-VNKDHWASSA-N

Network

Shown in network

Similarity

Show/Hide similarity panel

Reference Details

Reference Details

Reference Details

OpenFoodTox: component Hepta-2,4-dienal

GC-MS Spectrum