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Classification
Quality
Toxicity & Safety
Receptors

Compound Summary

General Compound Information

ethyl benzoate

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Description

Ethyl benzoate is a benzoate ester obtained by condensation of benzoic acid and ethanol. It is a volatile oil component found in ripe kiwifruit, cranberry juice, and palm kernel oil. It has a role as a flavouring agent, a fragrance and a volatile oil component. It is a benzoate ester and an ethyl ester.

Synonyms

ETHYL BENZOATE; 93-89-0; Benzoic acid, ethyl ester; Benzoic ether; Ethyl benzenecarboxylate;

Benzoic Acid Ethyl Ester;Benzoyl ethyl ether;Ethylester kyseliny benzoove;FEMA No. 2422;Benzoic acid-ethyl ester;CHEMBL510714;J115BRJ15H;BENZOIC ACID,ETHYL ESTER;DTXSID3038696;NSC-8884;Ethyl benzoate (natural);(Ethyl benzoate)tricarbonylchromium;NSC 8884;EINECS 202-284-3;Ethylester kyseliny benzoove [Czech];UNII-J115BRJ15H;AI3-01352;benzoic acid ethyl;MFCD00009109;Ethyl Benzoate Natural;Ethyl benzoate, >=99%;WLN: 2OVR;EC 202-284-3;ETHYL BENZOATE [MI];SCHEMBL55674;ETHYL BENZOATE [FCC];ETHYL BENZOATE [FHFI];ETHYL BENZOATE [INCI];Benzoic Acid Ethyl Ester-[d5];DTXCID1018696;Ethyl benzoate, puriss., 98%;FEMA 2422;NSC8884;CHEBI:156074;ZINC404389;Ethyl benzoate, analytical standard;Tox21_302021;BBL010500;BDBM50304448;STK025151;Ethyl benzoate, >=99%, FCC, FG;AKOS003596787;CAS-93-89-0;NCGC00255586-01;70750-02-6;70750-03-7;VS-02532;DB-002644;B0069;Ethyl benzoate, natural, >=99%, FCC, FG;FT-0622709;EN300-16131;Ethyl benzoate, Vetec(TM) reagent grade, 98%;A844728;Q421100;J-502070;Z53835169;F8880-7461;HYDROUS BENZOYL PEROXIDE IMPURITY C [EP IMPURITY];

FlavorDB ID

3424

PUBCHEM ID

Molecular Weight

150.17 Molecular Formula

C9H10O2

Openeye Can Smiles

CCOC(=O)C1=CC=CC=C1

IUPAC Inchikey

MTZQAGJQAFMTAQ-UHFFFAOYSA-N

Network

Similarity

CATEGORY	QUALITY	THRESHOLD	OCCURENCE	REFERENCE
smell	violet-like, flowery	3.529e-1 µmol/L	guava	details
smell	floral	3.529e-1 µmol/L	andes berry	details

Toxicity Summary
Link to the Distributed Structure-Searchable Toxicity (DSSTox) Database

Food Additive Safety (OFAS)
ETHYL BENZOATE is used for FLAVORING AGENT OR ADJUVANT. More food additive safty information please view GRAS report.

EFSA's chemical Hazards Database : OpenFoodTox
This compound is found in OpenFoodTox with the name: Ethyl benzoate

Reference point : Defined point on an experimental dose–response relationship for the critical effect. This term is synonymous to Point of departure (USA). Reference points include the lowest or no observed adverse effect level (LOAEL/NOAEL) or benchmark dose lower confidence limit (BDML), used to derive a reference value or Margin of Exposure in human and animal health risk assessment. In the ecological area, these include lethal dose (LD50), effect concentration (EC5/ECx), no (adverse) effect concentration/dose (NOEC/NOAEC/NOAED), no (adverse) effect level (NEL/NOAEL), hazard concentration (HC5/HCx) derived from a Species Sensitivity Distributions (SSD) for the ecosystem (EFSA Scientific Committee,2018). Citation: DOI 10.5281/zenodo.4740174

Reference point information of this compound is not available!

Reference Value

Reference Value : The estimated maximum dose (on a body mass basis) or the concentration of an agent to which an individual may be exposed over a specified period without appreciable risk. Reference values are established by applying an uncertainty factor to the reference point. Examples of reference values in human health include acceptable daily intake (ADI) for food and feed additives, and pesticides, tolerable upper intake levels (UL) for vitamins and minerals, and tolerable daily intake (TDI) for contaminants and food contact materials. For acute effects and operators, the acute reference dose (ARfD) and the acceptable operator exposure level (AOEL). In animal health and the ecological area, these include safe feed concentrations and the Predicted no effect concentration (PNEC) respectively (EFSA Scientific Committee, 2018). Citation: DOI 10.5281/zenodo.4740174

OUTPUT ID	ASSESSMENT	QUALIFIER	VALUE	UNIT	POPULATION
2281	TTC Cramer Class I	=	30	µg/kg bw/day	Consumers
2011	TTC Cramer Class I	=	30	µg/kg bw/day	Consumers
607	critical study not identified		0		Workers

Genotoxicity

Author	YEAR	OUTPUT ID	Genotoxicity
EFSA AFC	2008	2281	Negative
EFSA CEF	2009	2011	Negative
EFSA FEEDAP	2012	607	No data

EFSA Outputs

Output ID	Title	DOI	Published
607	Scientific Opinion on the safety and efficacy of benzyl alcohols, aldehydes, acids, esters and acetals (chemical group 23) when used as flavourings for all animal species	doi:10.2903/j.efsa.2012.2785	24Jul2012
2011	Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009).	doi:10.2903/j.efsa.2009.1025	11May2009
2281	Flavouring Group Evaluation 54 (FGE.54): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005). Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food	doi:10.2903/j.efsa.2008.835	31Oct2008

Receptors

Receptor information of this compound is not available!

Consensus Spectra

Spectrum Type	Spectrum View	Description	Polarity
Experimental GCMS	view	GCMS	positive

Content

Compound Summary

ethyl benzoate

Description

Synonyms

ETHYL BENZOATE; 93-89-0; Benzoic acid, ethyl ester; Benzoic ether; Ethyl benzenecarboxylate;

FlavorDB ID

3424

PUBCHEM ID

7165

Molecular Weight

150.17

Molecular Formula

C9H10O2

Openeye Can Smiles

CCOC(=O)C1=CC=CC=C1

IUPAC Inchikey

MTZQAGJQAFMTAQ-UHFFFAOYSA-N

Network

Shown in network

Similarity

Show/Hide similarity panel

Content

Compound Summary

ethyl benzoate

Description

Synonyms

ETHYL BENZOATE; 93-89-0; Benzoic acid, ethyl ester; Benzoic ether; Ethyl benzenecarboxylate;

FlavorDB ID

3424

PUBCHEM ID

7165

Molecular Weight

150.17

Molecular Formula

C9H10O2

Openeye Can Smiles

CCOC(=O)C1=CC=CC=C1

IUPAC Inchikey

MTZQAGJQAFMTAQ-UHFFFAOYSA-N

Network

Shown in network

Similarity

Show/Hide similarity panel

Reference Details

Reference Details

OpenFoodTox: component Ethyl benzoate

GC-MS Spectrum