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Compound Summary

General Compound Information

Costunolide

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Description

Costunolide is a germacranolide with anthelminthic, antiparasitic and antiviral activities. It has a role as an anthelminthic drug, an antiinfective agent, an antineoplastic agent, an antiparasitic agent, an antiviral drug and a metabolite. It is a germacranolide and a heterobicyclic compound.

Synonyms

Costunolide; 553-21-9; (+)-costunolide; Costunlide; Costunolid;

Costus lactone;CHEMBL86416;CHEBI:3900;(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one;(E,E)-6-alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oic acid gamma-lactone;NSC 106404;(10S,1R)-3,7-dimethyl-11-methylene-13-oxabicyclo[8.3.0]trideca-2,6-dien-12-one;(E,E)-germacra-1(10),4,11(13)-trien-12-oic acid, 6-alpha-hydroxy-gamma-lactone;(3aS,6E,10E)-3-Methylene-6,10-dimethyl-2,3,3abeta,4,5,8,9,11aalpha-octahydrocyclodeca[b]furan-2-one;(3aS,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one;(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one;melampolide;NSC106404;Costunolide,(S);SCHEMBL92714;Costunolide, >=97% (HPLC);HMS3269I17;HMS3413B19;HMS3677B19;(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3,3a,4,5,8,9-hexahydrocyclodeca[b]furan-2(11aH)-one;EX-A5462;HY-N0036;BDBM50411242;MFCD00210262;ZINC30726859;AKOS015840065;AKOS015969714;CS-1487;NCGC00381718-02;(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2-one;AC-28334;AS-17708;C09382;Q5175227;BRD-K26833429-001-01-0;(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2-one;Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, (3aS,6E,10E,11aR)-;

FlavorDB ID

4236

PUBCHEM ID

5281437

Molecular Weight

232.32

Molecular Formula

C15H20O2

Openeye Can Smiles

CC1=CCCC(=CC2C(CC1)C(=C)C(=O)O2)C

IUPAC Inchikey

HRYLQFBHBWLLLL-AHNJNIBGSA-N

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Similarity

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Compound Classification

Classification (Parent Nodes)

ClassyFire Ontology

Compound Quality

Quality information of this compound is not available!

Compound Toxicity

Toxicity and Food Additive Safety of this compound is not available!

Receptors

Receptor	REFERENCE	EC50 [µM]	Effective Concentration [µM]
TAS2R10	details	Activated	30.00
TAS2R14	details	Activated	30.00
TAS2R46	details	Activated	30.00

Consensus Spectra

Spectrum Type	Spectrum View	Description	Polarity
Experimental LCMS	view	LCMS_Positive	positive