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Compound Summary

General Compound Information

Sparteine

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Description

Sparteine is a quinolizidine alkaloid and a quinolizidine alkaloid fundamental parent.

Synonyms

Sparteine; (-)-Sparteine; 90-39-1; L-SPARTEINE; lupinidine;

(-)-Lupinidine;Lupinidin;Spartein;Sparteine [INN];6beta,7alpha,9alpha,11alpha-Pachycarpine;6-beta,7-alpha,9-alpha,11-alpha-Pachycarpine;Sparteinum;DTXSID4023591;CHEBI:28827;(7S,7aR,14S,14aS)-Tetradecahydro-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine;[7S-(7alpha,7aalpha,14alpha,14abeta)]-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine;298897D62S;Genisteine Alkaloid;7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-;DTXCID403591;Esparteina;Sparteina;Sparteine (-);7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-;(7S,7aS,14S,14aR)-dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine;7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, [7S-(7alpha,7aalpha,14alpha,14abeta)]-;SMR000059203;Sparteina [DCIT];Sparteinum [INN-Latin];Esparteina [INN-Spanish];(-)sparteine;CAS-90-39-1;UNII-298897D62S;(-) sparteine;NCGC00016346-01;sparteine-(-);Prestwick_426;EINECS 201-988-8;(+)-Spartein;SPARTEINE [MI];Prestwick3_000618;Sparteine (6CI,8CI);SPARTEINE [WHO-DD];SCHEMBL79043;BSPBio_000556;MLS000028889;MLS002207055;BPBio1_000612;CHEMBL1908847;HMS2096L18;AMY25811;ZINC1408502;Tox21_110386;MFCD00069653;s9142;AKOS016012217;Tox21_110386_1;CCG-266824;CS-W012901;DB06727;HY-W012185;(-)-Sparteine, >=98.0% (GC);NCGC00142614-01;NCGC00181124-02;7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-;S-6998;Q419552;(1S,2R,9S,10S)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane;(7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine;7,14-METHANO-2H,6H-DIPYRIDO(1,2-A:1',2'-E)(1,5)DIAZOCINE, DODECAHYDRO-, (7S,7AR,14S,14AS);

FlavorDB ID

4238

PUBCHEM ID

Molecular Weight

234.38 Molecular Formula

Not Available

Openeye Can Smiles

C1CCN2CC3CC(C2C1)CN4C3CCCC4

IUPAC Inchikey

SLRCCWJSBJZJBV-ZQDZILKHSA-N

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Similarity

Toxicity Summary
Link to the Distributed Structure-Searchable Toxicity (DSSTox) Database

EFSA's chemical Hazards Database : OpenFoodTox
This compound is found in OpenFoodTox with the name: (-)-Sparteine

Reference point : Defined point on an experimental dose–response relationship for the critical effect. This term is synonymous to Point of departure (USA). Reference points include the lowest or no observed adverse effect level (LOAEL/NOAEL) or benchmark dose lower confidence limit (BDML), used to derive a reference value or Margin of Exposure in human and animal health risk assessment. In the ecological area, these include lethal dose (LD50), effect concentration (EC5/ECx), no (adverse) effect concentration/dose (NOEC/NOAEC/NOAED), no (adverse) effect level (NEL/NOAEL), hazard concentration (HC5/HCx) derived from a Species Sensitivity Distributions (SSD) for the ecosystem (EFSA Scientific Committee,2018). Citation: DOI 10.5281/zenodo.4740174

Reference point information of this compound is not available!

Reference Value

Reference Value : The estimated maximum dose (on a body mass basis) or the concentration of an agent to which an individual may be exposed over a specified period without appreciable risk. Reference values are established by applying an uncertainty factor to the reference point. Examples of reference values in human health include acceptable daily intake (ADI) for food and feed additives, and pesticides, tolerable upper intake levels (UL) for vitamins and minerals, and tolerable daily intake (TDI) for contaminants and food contact materials. For acute effects and operators, the acute reference dose (ARfD) and the acceptable operator exposure level (AOEL). In animal health and the ecological area, these include safe feed concentrations and the Predicted no effect concentration (PNEC) respectively (EFSA Scientific Committee, 2018). Citation: DOI 10.5281/zenodo.4740174

Reference value information of this compound is not available!

Genotoxicity

Author	YEAR	OUTPUT ID	Genotoxicity
EFSA CONTAM	2019	3321	Not determined

EFSA Outputs

Output ID	Title	DOI	Published
3321	Scientific opinion on the risks for animal and human health related to the presence of quinolizidine alkaloids in feed and food, in particular in lupins and lupin-derived products	doi:10.2903/j.efsa.2019.5860	05Nov2019

Receptors

Receptor	REFERENCE	EC50 [µM]	Effective Concentration [µM]
TAS2R10	details	Activated	300.00
TAS2R46	details	Activated	300.00

Consensus Spectra

Spectrum Type	Spectrum View	Description	Polarity
Experimental LCMS	view	LCMS_Positive	positive

Content

Compound Summary

Sparteine

Description

Sparteine is a quinolizidine alkaloid and a quinolizidine alkaloid fundamental parent.

Synonyms

Sparteine; (-)-Sparteine; 90-39-1; L-SPARTEINE; lupinidine;

FlavorDB ID

4238

PUBCHEM ID

644020

Molecular Weight

234.38

Molecular Formula

Not Available

Openeye Can Smiles

C1CCN2CC3CC(C2C1)CN4C3CCCC4

IUPAC Inchikey

SLRCCWJSBJZJBV-ZQDZILKHSA-N

Network

Shown in network

Similarity

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Content

Compound Summary

Sparteine

Description

Sparteine is a quinolizidine alkaloid and a quinolizidine alkaloid fundamental parent.

Synonyms

Sparteine; (-)-Sparteine; 90-39-1; L-SPARTEINE; lupinidine;

FlavorDB ID

4238

PUBCHEM ID

644020

Molecular Weight

234.38

Molecular Formula

Not Available

Openeye Can Smiles

C1CCN2CC3CC(C2C1)CN4C3CCCC4

IUPAC Inchikey

SLRCCWJSBJZJBV-ZQDZILKHSA-N

Network

Shown in network

Similarity

Show/Hide similarity panel

OpenFoodTox: component (-)-Sparteine

Reference Details

Reference Details

GC-MS Spectrum